Perioperative Cardiovascular Care
This Special Communication discusses the changes in perioperative cardiovascular care during the past 3 decades and lessons learned to reduce morbidity and mortality.
View ArticleOn the Undiffusion of Established Practices
Everett Rogers’ classic monograph on the diffusion of innovations represents the process by which we adopt new ideas and practices as a smooth S-shaped curve. In this curve, the percentage of adoption...
View Article2014 Atrial Fibrillation Guideline Revisions
This study examines the change in proportion of atrial fibrillation patients eligible for anticoagulation before and after the 2014 revision of the AHA/ACC/HRS anticoagulation guidelines.
View ArticleWells Score for Inpatients With DVT
This prospective study of inpatients with suspected lower-extremity deep vein thrombosis showed that the Wells score performed only slightly better than chance at assessing risk for deep vein...
View ArticleThe Wells Deep Vein Thrombosis Score for Inpatients
This Invited Commentary discusses the poor utility of the Wells score for deep vein thrombosis in inpatients and suggests alternative approaches to stratify the risk of deep vein thrombosis.
View ArticleIntra-Aortic Balloon Pump in Myocardial Infarction
In this meta-analysis, intra-aortic balloon pump therapy was not found to improve mortality among patients with acute myocardial infarction in randomized clinical trials, regardless of whether patients...
View ArticleReporting of Limitations of Observational Research
Observational research is abundant and influences clinical practice, in part via publication in high-impact journals and dissemination by news media. However, it frequently generates unreliable...
View ArticleAssociation Between Surrogate End Points and Survival in Oncology
This systematic review summarizes the available published evidence on associations between patient survival and surrogate end points used in medical oncology trials and find the correlations to be...
View ArticlePrevalence of Overweight and Obesity in the United States, 2007-2012
Overweight and obesity are associated with various chronic conditions. These conditions are considerable health care and societal burdens, yet could potentially be averted by preventing weight gain and...
View ArticleExcessive Antibiotic Use in Nursing Homes
In the United States, on any given day, approximately 1.4 million people reside in more than 15 000 nursing homes (NHs). As a testament to the burgeoning post–acute care population, approximately 3.3...
View ArticleBreast Cancer Screening, Incidence, and Mortality Across US Counties
This ecological study using data from the SEER cancer registries examines the associations between rates of mammography screening and the incidence of breast cancer, mortality from breast cancer, and...
View ArticleCognitive Behavioral Therapy for Comorbid Insomnia
This meta-analysis evaluates the use of cognitive behavioral therapy for treatment of insomnia in patients with comorbid medical or psychiatric conditions.
View ArticleEffect of Screening Mammography on Cancer Incidence and Mortality
With increasing availability of massive quantities of health care data and advances in technology for data analyses, novel investigations of health delivery and outcomes are proliferating. In this...
View ArticleTreating Insomnia With Medical and Psychiatric Comorbidities
Insomnia is a common condition. It is estimated that approximately 30% of the population experiences some symptom of insomnia, and approximately 5% to 15% of these individuals are likely to meet...
View ArticleIndustry Relationships Among Academic IRB Members
This survey study examined the nature, extent, and perceived consequences of industry relationships among institutional review board members in academic health centers and compared the results with...
View ArticleAdvancing Science in the Service of Humanity
Is human experimentation ever ethically permissible? Are human studies always and inevitably exploitative? Since the release of the Belmont Report in the United States in 1979, the response to these...
View ArticleNationwide Population Science: Lessons From Taiwan
Large population-based studies can inform us on the prevalence, incidence, natural history, treatment, correlates, and associations of disease, as well as the pattern of health care utilization. A...
View ArticleDisclosure of Boxed Warnings to Research Participants
This database review assesses the disclosure to study participants of boxed warning risks on consent forms.
View ArticleExcessive Antibiotic Use in Nursing Homes
In the United States, on any given day, approximately 1.4 million people reside in more than 15 000 nursing homes (NHs). As a testament to the burgeoning post–acute care population, approximately 3.3...
View ArticleAssociation Between Surrogate End Points and Survival in Oncology
This systematic review summarizes the available published evidence on associations between patient survival and surrogate end points used in medical oncology trials and find the correlations to be...
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