Prevalence of Overweight and Obesity in the United States, 2007-2012
Overweight and obesity are associated with various chronic conditions. These conditions are considerable health care and societal burdens, yet could potentially be averted by preventing weight gain and...
View ArticleModeling the Health Effects and “Costs” of Expanding e-Cigarette Sales
The results of this modeling study suggest that widespread promotion of e-cigarettes may have harmful population-level health effects, depending on how the e-cigarette market might develop, potential...
View ArticleDisclosure of Boxed Warnings to Research Participants
This database review assesses the disclosure to study participants of boxed warning risks on consent forms.
View ArticleNationwide Population Science: Lessons From Taiwan
Large population-based studies can inform us on the prevalence, incidence, natural history, treatment, correlates, and associations of disease, as well as the pattern of health care utilization. A...
View ArticleIndustry Relationships Among Academic IRB Members
This survey study examined the nature, extent, and perceived consequences of industry relationships among institutional review board members in academic health centers and compared the results with...
View ArticleAdvancing Science in the Service of Humanity
Is human experimentation ever ethically permissible? Are human studies always and inevitably exploitative? Since the release of the Belmont Report in the United States in 1979, the response to these...
View ArticleBreast Cancer Screening, Incidence, and Mortality Across US Counties
This ecological study using data from the SEER cancer registries examines the associations between rates of mammography screening and the incidence of breast cancer, mortality from breast cancer, and...
View ArticleCognitive Behavioral Therapy for Comorbid Insomnia
This meta-analysis evaluates the use of cognitive behavioral therapy for treatment of insomnia in patients with comorbid medical or psychiatric conditions.
View ArticleEffect of Screening Mammography on Cancer Incidence and Mortality
With increasing availability of massive quantities of health care data and advances in technology for data analyses, novel investigations of health delivery and outcomes are proliferating. In this...
View ArticleTreating Insomnia With Medical and Psychiatric Comorbidities
Insomnia is a common condition. It is estimated that approximately 30% of the population experiences some symptom of insomnia, and approximately 5% to 15% of these individuals are likely to meet...
View ArticleReporting of Limitations of Observational Research
This research letter assesses the reporting limitations of observational studies published in major internal medicine journals and associated news stories, specifically focusing on inference of...
View ArticlePatient Characteristics and Differences in Readmission Rates
This survey data–based study from the Health and Retirement Study and linked Medicare claims for participants who were hospitalized from 2009 to 2012 assessed the extent to which a comprehensive set of...
View ArticleUnplanned Early Hospital Readmissions as Health Care Quality Indicator
High-quality health care is an important goal for all societies. Most people would agree that societies should reward health care providers or organizations providing high-quality care while those...
View ArticleTesting US FDA “Breakthrough” Language
This randomized trial explores why press releases with neutral terms—and that routinely explain the limited evidence supporting accelerating approval—might help consumers make more accurate judgments...
View ArticleProducing Evidence to Reduce Low-Value Care
This Viewpoint explores efforts to generate evidence that will distinguish between high- and low-value care.
View ArticlePhysicians and Insider Trading
This Special Communication characterizes the relationships that often exist between physicians and corporate leaders of medical and technical companies and details strategies to minimize insider...
View ArticleTreating Influenza With Neuraminidase Inhibitors
This short review of the literature on neuraminidase inhibitor effectiveness on influenza virus concludes that, while randomized clinical trials are lacking, observation data suggest benefit,...
View ArticleCancer Drugs Approved on the Basis of a Surrogate End Point
This review of approvals of cancer drugs based on a surrogate end point by the US Food and Drug Administration assesses the postmarketing findings for overall survival.
View ArticleTesting US FDA “Breakthrough” Language
This randomized trial explores why press releases with neutral terms—and that routinely explain the limited evidence supporting accelerating approval—might help consumers make more accurate judgments...
View ArticlePatient Characteristics and Differences in Readmission Rates
This survey data–based study from the Health and Retirement Study and linked Medicare claims for participants who were hospitalized from 2009 to 2012 assessed the extent to which a comprehensive set of...
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